Variceal bleeding
نویسنده
چکیده
Approximately 90% of patients with cirrhosis will have developed gastro-oesophageal varices within 10 yr. Oesophageal variceal haemorrhage is a devastating complication of cirrhosis with mortality as high as 25–50%. Therefore, prophylactic measures before the first bleed are crucial. If patients survive a variceal bleed, there is approximately a 70% risk that they will have a further bleed within the following 2 yr. Measures to minimize the risk of re-bleeding have been investigated and hospital mortality has decreased from 42% in 1980 to 14% in 2000. This review describes the factors involved in variceal haemorrhage, management of an acute bleed, and current opinions on appropriate prophylactic measures.
منابع مشابه
تعیین ارزش پیش آگهی معیار بالینی MELD و CTP در خون‌ریزی از واریس مری در بیماران سیروتیک بستری شده در بخش گوارش بیمارستان امام خمینی ارومیه در سال‌های 87-88
Background & Aims : Risk factors for r ebleeding following acute variceal haemorrhage are incompletely understood. The aim of this study was to determine the predictor validity of model for end stage liver disease (MELD) score and Child-Turcotte-Pugh (CTP) in acute variceal bleeding and rebleeding. Method : The study included 92 cirrhotic patients of Imam Khomeini hospital. The predictive c...
متن کاملعوامل پیش‌بینی کننده خون‌ریزی مجدد در خون‌ریزی از واریس مری در بیماران بستری در بخش گوارش بیمارستان امام خمینی 87-86
Background and Objective: Esophageal variceal bleeding is associated with a high mortality rate and expensive hospitalization costs. By diagnosing predicting factors of rebleeding at admission, and proper course of action, we can minimize the rates of mortality rebleeding. The aim of this study was to determine the predicting factors of rebleeding in patients hospitalized because of variceal he...
متن کاملVariceal pressure is a strong predictor of variceal haemorrhage in patients with cirrhosis as well as in patients with non-cirrhotic portal hypertension.
BACKGROUND Variceal pressure is a strong predictor for a first variceal bleed in patients with cirrhosis. AIMS To evaluate whether variceal pressure is also a determinant of the risk of a first variceal bleed in patients with non-cirrhotic portal hypertension. METHODS Variceal pressure was measured non-invasively in 25 patients with non-cirrhotic portal hypertension and large varices while ...
متن کاملVariceal bleeding in cirrhotic patients: risk factors, evolution, treatment
OBJECTIVES The aim of this study was to monitor the risk factors that trigger variceal bleeding in cirrhotic patients, assess the severity of the bleeding and the efficacy of the endoscopic hemostasis techniques, as well as the recurrence of bleeding episodes and the mortality rate. MATERIALS AND METHODS The current study was a prospective one, and it was conducted in the period November 2004...
متن کاملChanges in the Clinical Outcomes of Variceal Bleeding in Cirrhotic Patients: A 10-Year Experience in Gangwon Province, South Korea
BACKGROUND/AIMS Variceal rupture is one of the main causes of mortality in cirrhotic patients. However, there are limited data on the long-term outcomes of variceal bleeding. METHODS We investigated the incidence and mortality of variceal bleeding at three endoscopic centers in Gangwon province during 3 periods (August 1996 to July 1997, August 2001 to July 2002, and August 2006 to July 2007)...
متن کاملEndoscopic band ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhotic patients with high risk esophageal varices.
BACKGROUND Gastroesophageal variceal bleeding is a common complication of portal hypertension. Current guidelines recommend thorn-blockers for primary prophylaxis. However, evidence suggests that endoscopic variceal ligation (EVL) reduce bleeding episodes. AIMS To compare endoscopic EVL with propranolol (PPL) for primary prophylaxis of variceal bleeding. METHODS We conducted a randomized co...
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